Replication studies on human immunodeficiency virus 1 (HIV-1) rely on a few laboratory strains that are divergent from dominant HIV-1 subtypes in the epidemic.Several phenotypic differences between diverse HIV-1 isolates and subtypes could affect vaccine development Serving Spoons and treatment, but this research field lacks robust cloning/virus pr
Abstract Background Dengue virus infection results in a broad spectrum of clinical outcomes, ranging from asymptomatic infection through to severe dengue.Although prior infection with another viral serotype, i.e.secondary dengue, is known to be an important factor influencing disease severity, current methods to determine primary versus secondary i
Abstract Background Nursing shortages are an ongoing concern for neonatal units, with many struggling to meet recommended nurse to patient ratios.Workforce data underlines the high proportion of neonatal nurses nearing retirement and a reduced number of nurses joining the profession.In order to recommend strategies to increase recruitment and reten
In this work, we investigate optimality principles behind synthesis strategies for protein complexes using a dynamic optimization approach.We show that the cellular capacity of protein synthesis has a strong influence on optimal synthesis strategies reaching from a simultaneous to a sequential synthesis of the subunits of a protein complex.Sequenti
Motorcyclists failing to wear helmets is one of the main reasons why people die in these kinds of crashes.Traditional approaches Serving Spoons to ensuring motorcycle riders wear helmets include traffic police manually monitoring intersections or using CCTV footage to detect riders who are not wearing helmets.These techniques, however, necessitate